Shanghai Clirik Machinery Co.,Ltd
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Pharmaceutical and Cosmetic Solutions
The pharmaceutical and cosmetic industries have extremely stringent standards for the purity, fineness, and activity of powder materials. Our equipment can handle the processing requirements of pharmaceuticals (such as nimodipine, procaine, penicillin, amoxicillin, aspirin, and ibuprofen) and cosmetic raw materials for powders requiring “high purity, ultra-fine fineness, and heat-sensitive protection,” completing a one-stop operation from raw material pretreatment to nano-level grinding. After processing by our grinding equipment, these materials can significantly improve the dissolution and bioavailability of drugs, or enhance the skin feel and coverage of cosmetics. Our equipment can transform raw pharmaceutical materials and mineral powders into highly active, sterile, high-quality powders, meeting the high standards required for pharmaceutical formulations and high-end beauty products.
Pharmaceutical and Cosmetic Solutions
The pharmaceutical and cosmetic industries have extremely stringent standards for the purity, fineness, and activity of powder materials. Our equipment can handle the processing requirements of pharmaceuticals (such as nimodipine, procaine, penicillin, amoxicillin, aspirin, and ibuprofen) and cosmetic raw materials for powders requiring “high purity, ultra-fine fineness, and heat-sensitive protection,” completing a one-stop operation from raw material pretreatment to nano-level grinding. After processing by our grinding equipment, these materials can significantly improve the dissolution and bioavailability of drugs, or enhance the skin feel and coverage of cosmetics. Our equipment can transform raw pharmaceutical materials and mineral powders into highly active, sterile, high-quality powders, meeting the high standards required for pharmaceutical formulations and high-end beauty products.
+8613512155195
Nimodipine
Procaine
Penicillin
Amoxicillin
Aspirin
Ibuprofen
Cosmetics
Nimodipine
Procaine
Penicillin
Amoxicillin
Aspirin
Ibuprofen
Cosmetics
Process & Solutions
Targeting the production characteristics of the pharmaceutical and cosmetic industries, which require powders to be “sterile and safe, with extremely narrow particle size and crystal form protection,” our equipment can complete the entire process of crushing, grinding, grading, powder collection, and packaging, ensuring that the powders achieve optimal performance in end applications.
Stage 1：Crushing
Raw materials (such as tablets and crystalline granules) need to undergo preliminary crushing to control the particle size within the range of 10mm-20mm, meeting the feeding standards of the ultrafine grinding mill and preventing equipment blockage due to excessively large particles.
Stage 2：Grinding
The pre-treated material is fed into the raw material hopper by an elevator, and then uniformly and quantitatively fed into the grinding chamber of the mill by a vibrating feeder. Our CLJM series airflow mills excel in producing micron- or even nano-sized ultrafine powders required for pharmaceuticals (nimodipine, amoxicillin, etc.) and cosmetics. This equipment utilizes supersonic airflow to self-grind materials, eliminating the need for mechanical grinding media and avoiding metal contamination. Simultaneously, the airflow expansion and heat absorption effect enables low-temperature grinding, effectively preventing the degradation and denaturation of heat-sensitive drugs (such as penicillin and ibuprofen) and active ingredients in cosmetics, preserving the material’s crystal structure and efficacy.
Stage 3：Classification
The ground material enters a high-efficiency turbine classifier with the airflow. By adjusting the rotation speed of the classifying wheel, the required particle size range (e.g., D97≤5μm) can be precisely cut. Qualified fine powder enters the collection system with the airflow, while coarse particles automatically fall back into the grinding chamber for further grinding, forming a closed-loop cycle. This ensures a concentrated particle size distribution in the finished product, free of coarse impurities, guaranteeing the stability of drug release and the fineness of the cosmetic.
Stage 4：Powder Collection
The micro-powder meeting the fineness requirements enters a pulse dust collector for gas-solid separation. The entire system operates under negative pressure, equipped with a long-bag low-pressure pulse dust collector. Dust emission concentrations are far below national standards, with a collection efficiency of up to 99.9%. The collected finished powder is discharged through a discharge valve and enters the finished product silo, achieving dust-free production.
Stage 5：Packaging
The finished powder is packaged into 25kg bags or ton bags using an automatic packaging machine. The entire process is carried out in a closed system to ensure no dust pollution and guarantee the hygiene and safety of the finished product during transportation and storage.
Process & Solutions
Targeting the production characteristics of the pharmaceutical and cosmetic industries, which require powders to be “sterile and safe, with extremely narrow particle size and crystal form protection,” our equipment can complete the entire process of crushing, grinding, grading, powder collection, and packaging, ensuring that the powders achieve optimal performance in end applications.
Stage 1：Crushing
Raw materials (such as tablets and crystalline granules) need to undergo preliminary crushing to control the particle size within the range of 10mm-20mm, meeting the feeding standards of the ultrafine grinding mill and preventing equipment blockage due to excessively large particles.
Stage 2：Grinding
The pre-treated material is fed into the raw material hopper by an elevator, and then uniformly and quantitatively fed into the grinding chamber of the mill by a vibrating feeder. Our CLJM series airflow mills excel in producing micron- or even nano-sized ultrafine powders required for pharmaceuticals (nimodipine, amoxicillin, etc.) and cosmetics. This equipment utilizes supersonic airflow to self-grind materials, eliminating the need for mechanical grinding media and avoiding metal contamination. Simultaneously, the airflow expansion and heat absorption effect enables low-temperature grinding, effectively preventing the degradation and denaturation of heat-sensitive drugs (such as penicillin and ibuprofen) and active ingredients in cosmetics, preserving the material’s crystal structure and efficacy.
Stage 3：Classification
The ground material enters a high-efficiency turbine classifier with the airflow. By adjusting the rotation speed of the classifying wheel, the required particle size range (e.g., D97≤5μm) can be precisely cut. Qualified fine powder enters the collection system with the airflow, while coarse particles automatically fall back into the grinding chamber for further grinding, forming a closed-loop cycle. This ensures a concentrated particle size distribution in the finished product, free of coarse impurities, guaranteeing the stability of drug release and the fineness of the cosmetic.
Stage 4：Powder Collection
The micro-powder meeting the fineness requirements enters a pulse dust collector for gas-solid separation. The entire system operates under negative pressure, equipped with a long-bag low-pressure pulse dust collector. Dust emission concentrations are far below national standards, with a collection efficiency of up to 99.9%. The collected finished powder is discharged through a discharge valve and enters the finished product silo, achieving dust-free production.
Stage 5：Packaging
The finished powder is packaged into 25kg bags or ton bags using an automatic packaging machine. The entire process is carried out in a closed system to ensure no dust pollution and guarantee the hygiene and safety of the finished product during transportation and storage.
You May Concerned (FAQ)
1. About Secondary Agglomeration, how can you ensure that ultra-fine powder (above 2500 mesh) remains perfectly dispersed and does not clump during downstream masterbatch extrusion after the coating process?
Our CLG vortex chamber utilizes high-speed shearing force to de-agglomerate particles while simultaneously applying a uniform coating, ensuring superior dispersibility in downstream polymers
2. About High Oil Absorption Costs, how can you effectively reduce the oil absorption of your powder to save on expensive resin consumption in your plastic manufacturing?
CLIRIK’s precision chemical bonding creates a complete hydrophobic layer on each particle, significantly dropping oil absorption values and optimizing resin compatibility.
3. About Purity & Whiteness Risks, how do you prevent iron contamination during high-pressure grinding to ensure the premium whiteness required for high-end paper and plastic fillers?
We utilize high-grade wear-resistant ceramic or alloy liners combined with a fully sealed negative pressure system to eliminate metal friction contamination entirely
4. About Precise Particle Control (PSD), how can you achieve a steep and stable particle size distribution with a precise D97 cutoff to meet strict modern industrial standards?
Our integrated high-efficiency turbine classifiers feature adjustable frequency control, allowing for a sharp D97 cutoff that meets the strictest industrial consistency standards.
5. About Moisture Interference, how do you handle raw materials with varying moisture levels to prevent the failure of chemical bonding during the coating process?
CLIRIK systems feature intelligent pre-conditioning and synchronized feeding to maintain optimal humidity levels (<0.5%), ensuring a perfect and stable chemical reaction.
6. About Inconsistent Batch Quality, how can you eliminate the variability of manual operations to ensure every batch of modified powder meets your strict specifications?
Full PLC automation monitors and synchronizes all production parameters in real-time, removing human error and ensuring 100% batch-to-batch stability.
7. About Chemical Agent Waste,how can you achieve precise agent-to-powder ratios to avoid wasting expensive chemicals while maintaining a 98%+ activation index?
Our synchronized dosing system atomizes agents based on exact material flow, achieving a 98%+ activation index with minimal chemical consumption.
8. About Excessive Maintenance Downtime, how can you minimize the frequency of wear-part replacements and prevent unplanned production halts in heavy-duty grinding?
By using ultra-hard alloy components and a modular “Easy-Access” design, CLIRIK extends maintenance intervals and allows for rapid replacement of wearing parts.
9. About Energy Efficiency Gaps, compared to traditional mills, how can you significantly reduce the power consumption per ton of fine powder while maintaining high-capacity output?
Advanced grinding curves and optimized system air resistance reduce power consumption by up to 30% per ton while maintaining higher capacity output.
10. About Environmental Dust Leakage, how do you maintain a clean factory environment and meet strict environmental regulations during high-speed, large-scale powder processing?
A fully sealed negative pressure operation combined with new-generation impulse bag filters ensures zero dust leakage and a zero-emission workshop.
You May Concerned (FAQ)
1.About Secondary Agglomeration, how can you ensure that ultra-fine powder (above 2500 mesh) remains perfectly dispersed and does not clump during downstream masterbatch extrusion after the coating process?
The CLIRIK Answer: Our CLG vortex chamber utilizes high-speed shearing force to de-agglomerate particles while simultaneously applying a uniform coating, ensuring superior dispersibility in downstream polymers
2.About High Oil Absorption Costs, how can you effectively reduce the oil absorption of your powder to save on expensive resin consumption in your plastic manufacturing?
CLIRIK’s precision chemical bonding creates a complete hydrophobic layer on each particle, significantly dropping oil absorption values and optimizing resin compatibility.
3.About Purity & Whiteness Risks, how do you prevent iron contamination during high-pressure grinding to ensure the premium whiteness required for high-end paper and plastic fillers?
The CLIRIK Answer: We utilize high-grade wear-resistant ceramic or alloy liners combined with a fully sealed negative pressure system to eliminate metal friction contamination entirely
4.About Precise Particle Control (PSD), how can you achieve a steep and stable particle size distribution with a precise D97 cutoff to meet strict modern industrial standards?
Our integrated high-efficiency turbine classifiers feature adjustable frequency control, allowing for a sharp D97 cutoff that meets the strictest industrial consistency standards.
5.About Moisture Interference, how do you handle raw materials with varying moisture levels to prevent the failure of chemical bonding during the coating process?
CLIRIK systems feature intelligent pre-conditioning and synchronized feeding to maintain optimal humidity levels (<0.5%), ensuring a perfect and stable chemical reaction.
6.About Inconsistent Batch Quality, how can you eliminate the variability of manual operations to ensure every batch of modified powder meets your strict specifications?
Full PLC automation monitors and synchronizes all production parameters in real-time, removing human error and ensuring 100% batch-to-batch stability.
7.About Chemical Agent Waste,how can you achieve precise agent-to-powder ratios to avoid wasting expensive chemicals while maintaining a 98%+ activation index?
Our synchronized dosing system atomizes agents based on exact material flow, achieving a 98%+ activation index with minimal chemical consumption.
8.About Excessive Maintenance Downtime, how can you minimize the frequency of wear-part replacements and prevent unplanned production halts in heavy-duty grinding?
By using ultra-hard alloy components and a modular “Easy-Access” design, CLIRIK extends maintenance intervals and allows for rapid replacement of wearing parts.
9.About Energy Efficiency Gaps, compared to traditional mills, how can you significantly reduce the power consumption per ton of fine powder while maintaining high-capacity output?
Advanced grinding curves and optimized system air resistance reduce power consumption by up to 30% per ton while maintaining higher capacity output.
10.About Environmental Dust Leakage, how do you maintain a clean factory environment and meet strict environmental regulations during high-speed, large-scale powder processing?
A fully sealed negative pressure operation combined with new-generation impulse bag filters ensures zero dust leakage and a zero-emission workshop.
Equipment We Can Provide
CLJM Series Jet Mill
Supersonic Jet Milling System: Utilizes supersonic airflow from Laval nozzles for autogenous grinding without mechanical contact. Integrated with high-precision centrifugal classifying, it ensures narrow particle size distribution and high purity for premium powder processing.
Equipment We Can Provide
CLJM Series Jet Mill
Supersonic Jet Milling System: Utilizes supersonic airflow from Laval nozzles for autogenous grinding without mechanical contact. Integrated with high-precision centrifugal classifying, it ensures narrow particle size distribution and high purity for premium powder processing.
Click To Get The Solution For Free
Click To Get The Solution For Free
Are You Facing The Following Problems?
paired Activity:
Excessive temperature during processing can cause heat-sensitive ingredients such as antibiotics or vitamins to become ineffective.
Insufficient Purity:
Equipment wear can lead to the introduction of metallic impurities, making it impossible to pass heavy metal testing in pharmaceuticals or cosmetics.
Insufficient Fineness:
Powder particle size can result in slow drug dissolution, poor absorption, or a rough texture in cosmetics.
Batch Variation:
Uneven particle size distribution can affect the efficacy stability of drugs or the color consistency of cosmetics.
Environmental Pollution:
Dust spillage not only wastes raw materials but also poses a risk of failing GMP inspections.
Are You Facing The Following Problems?
paired Activity:
Excessive temperature during processing can cause heat-sensitive ingredients such as antibiotics or vitamins to become ineffective.
Insufficient Purity:
Equipment wear can lead to the introduction of metallic impurities, making it impossible to pass heavy metal testing in pharmaceuticals or cosmetics.
Insufficient Fineness:
Powder particle size can result in slow drug dissolution, poor absorption, or a rough texture in cosmetics.
Batch Variation:
Uneven particle size distribution can affect the efficacy stability of drugs or the color consistency of cosmetics.
Environmental Pollution:
Dust spillage not only wastes raw materials but also poses a risk of failing GMP inspections.
We Have Already Solved The Problem For Them
Turning complex grinding challenges into high-performance operational success
Clirik HGM Series Ultrafine Mill has been successfully integrated into a production line in Abu Dhabi, United Arab Emirates
To meet the client’s demand in Abu Dhabi, United Arab Emirates, for high-precision 10-micron (D97) calcium carbonate, our experts engineered an eco-friendly production line focused on strict particle size control and zero dust emission. By integrating advanced ball milling units, precision classifiers, and powder coating equipment, the system ensures uniform particle distribution and minimal material loss, delivering a high-quality, sustainable solution for premium industrial powder applications.
Clirik CLUM Series Vertical Mill was officially commissioned for high-end powder grinding in Ho Chi Minh City, Vietnam
By incorporating advanced vertical grinding mills and smart separators, our technical team customized a high-efficiency processing circuit in Ho Chi Minh City, Vietnam. This project was specifically designed to satisfy local requirements for 15-micron (D97) mineral fillers through rigorous fineness management and clean-air operation. The facility guarantees consistent product quality and optimized power savings, providing a top-tier, eco-conscious outcome for specialized manufacturing sectors.
Clirik HGM Series Ultrafine Mill has been successfully integrated into a production line in Abu Dhabi, United Arab Emirates
Achieving homogeneous output and exceptional operational reliability was the core objective for a new manufacturing setup developed in Johannesburg, South Africa. Our specialists deployed industrial pulverizing machinery and high-speed grading units to fulfill the client’s need for heavy-duty 25-micron (D97) limestone grinding. Dedicated to precise granulometry and maximum environmental protection, the setup yields a superior, resource-efficient platform for diverse mineral processing industries.
We Have Already Solved The Problem For Them
Turning complex grinding challenges into high-performance operational success
Clirik HGM Series Ultrafine Mill has been successfully integrated into a production line in Abu Dhabi, United Arab Emirates
To meet the client’s demand in Abu Dhabi, United Arab Emirates, for high-precision 10-micron (D97) calcium carbonate, our experts engineered an eco-friendly production line focused on strict particle size control and zero dust emission. By integrating advanced ball milling units, precision classifiers, and powder coating equipment, the system ensures uniform particle distribution and minimal material loss, delivering a high-quality, sustainable solution for premium industrial powder applications.
Clirik CLUM Series Vertical Mill was officially commissioned for high-end powder grinding in Ho Chi Minh City, Vietnam
By incorporating advanced vertical grinding mills and smart separators, our technical team customized a high-efficiency processing circuit in Ho Chi Minh City, Vietnam. This project was specifically designed to satisfy local requirements for 15-micron (D97) mineral fillers through rigorous fineness management and clean-air operation. The facility guarantees consistent product quality and optimized power savings, providing a top-tier, eco-conscious outcome for specialized manufacturing sectors.
Clirik HGM Series Ultrafine Mill has been successfully integrated into a production line in Abu Dhabi, United Arab Emirates
Achieving homogeneous output and exceptional operational reliability was the core objective for a new manufacturing setup developed in Johannesburg, South Africa. Our specialists deployed industrial pulverizing machinery and high-speed grading units to fulfill the client’s need for heavy-duty 25-micron (D97) limestone grinding. Dedicated to precise granulometry and maximum environmental protection, the setup yields a superior, resource-efficient platform for diverse mineral processing industries.
Not Only The Mill Manufacturer,
But Also The Project Provider.
Not Only The Mill Manufacturer,
But Also The Project Provider.
Core Manufacturing Edge
High Purity Ultrafine • Activity Protection • Safe and Sterile
01.Superior Activity Protection
The CLJM airflow mill uses cold grinding technology, with extremely low temperatures within the grinding chamber, effectively preventing high temperatures from damaging the bioactivity of materials. It is particularly suitable for processing heat-sensitive drugs and cosmetic raw materials.
02.Extremely High Finished Product Purity
The equipment uses no mechanical grinding media; materials are pulverized through self-collision, eliminating metal contact contamination and ensuring extremely low iron content in the finished product, meeting pharmaceutical and food-grade high purity standards.
03.Concentrated Particle Size Distribution
Equipped with a high-efficiency turbine classifier, the fineness of the finished product is flexibly and precisely adjusted, eliminating coarse particles and ensuring high dissolution rates for pharmaceuticals and high fineness for cosmetics.
04.Low Energy Consumption and High Efficiency
Optimized equipment structure design results in high airflow utilization and grinding efficiency, saving over 30% energy compared to traditional ball mills, significantly reducing the electricity cost per unit product.
05.Fully Enclosed Dust-Free Production
The entire equipment operates under negative pressure and is equipped with a high-efficiency pulse dust removal system, preventing dust spillage and meeting GMP workshop and environmental hygiene and safety requirements.
06.Intelligent Control
Equipped with a PLC intelligent control system, it enables remote monitoring and automated operation, precisely controlling grinding pressure and temperature to ensure highly consistent product quality. VII. Other Solutions
Core Manufacturing Edge
High Purity Ultrafine • Activity Protection • Safe and Sterile
01.Superior Activity Protection
The CLJM airflow mill uses cold grinding technology, with extremely low temperatures within the grinding chamber, effectively preventing high temperatures from damaging the bioactivity of materials. It is particularly suitable for processing heat-sensitive drugs and cosmetic raw materials.
02.Extremely High Finished Product Purity
The equipment uses no mechanical grinding media; materials are pulverized through self-collision, eliminating metal contact contamination and ensuring extremely low iron content in the finished product, meeting pharmaceutical and food-grade high purity standards.
03.Concentrated Particle Size Distribution
Equipped with a high-efficiency turbine classifier, the fineness of the finished product is flexibly and precisely adjusted, eliminating coarse particles and ensuring high dissolution rates for pharmaceuticals and high fineness for cosmetics.
04.Low Energy Consumption and High Efficiency
Optimized equipment structure design results in high airflow utilization and grinding efficiency, saving over 30% energy compared to traditional ball mills, significantly reducing the electricity cost per unit product.
05.Fully Enclosed Dust-Free Production
The entire equipment operates under negative pressure and is equipped with a high-efficiency pulse dust removal system, preventing dust spillage and meeting GMP workshop and environmental hygiene and safety requirements.
06.Intelligent Control
Equipped with a PLC intelligent control system, it enables remote monitoring and automated operation, precisely controlling grinding pressure and temperature to ensure highly consistent product quality. VII. Other Solutions
Get professional services through
online consultation
Get professional services through
online consultation
Why Choose Us
Empowering Quality, Enhancing Efficiency
20+ Years of Expertise
With 20+ years in powder grinding processing, we deeply understand every ore’s traits. From mechanical design to smart systems, our decades of expertise help you avoid industry pitfalls and provide the most stable, proven equipment solutions.
3600+ Global Site Projects
With 3600+ active sites worldwide, our mills excel from humid tropics to extreme continental climates. This vast field experience allows us to replicate success quickly, building optimized production lines that perfectly suit your specific local working conditions.
Material Testing & Trials
We offer material testing to accurately measure fineness, output, and power use for your specific ores. You can witness the trial runs firsthand, ensuring the final product quality perfectly meets your expectations before the equipment is even put into operation.
Pro Installation & Support
Our experienced team handles everything from foundation guidance to operator training. Wherever you are, our engineers provide professional online and onsite support to ensure a fast startup and efficient operation, resolving all your concerns after the sale.
Why Choose Us
Empowering Quality,
Enhancing Efficiency
20+ Years of Expertise
With 20+ years in powder grinding processing, we deeply understand every ore’s traits. From mechanical design to smart systems, our decades of expertise help you avoid industry pitfalls and provide the most stable, proven equipment solutions.
3600+ Global Site Projects
With 3600+ active sites worldwide, our mills excel from humid tropics to extreme continental climates. This vast field experience allows us to replicate success quickly, building optimized production lines that perfectly suit your specific local working conditions.
Material Testing & Trials
We offer material testing to accurately measure fineness, output, and power use for your specific ores. You can witness the trial runs firsthand, ensuring the final product quality perfectly meets your expectations before the equipment is even put into operation.
Pro Installation & Support
Our experienced team handles everything from foundation guidance to operator training. Wherever you are, our engineers provide professional online and onsite support to ensure a fast startup and efficient operation, resolving all your concerns after the sale.
CONTACT US
Submit Your Needs for
Expert Consultation
Every mineral has its unique value. Share your material specs and capacity
needs, and CLIRIK experts will tailor a cost-effective grinding solution to ensure
your project’s successful operation.
Address
No.19, Fuqing Rd, Pudong
New Area, Shanghai, China.
Find Us On :
Let us talk, send us a message today!
Submit Your Needs for
Expert Consultation
Every mineral has its unique value. Share your material specs and capacity
needs, and CLIRIK experts will tailor a cost-effective grinding solution to ensure
your project’s successful operation.
Address
No.19, Fuqing Rd, Pudong
New Area, Shanghai, China.
Find Us On :
Let us talk, send us a message today!
Other Industry Solutions
Versatile Solutions for Diverse Industries
Other Industry Solutions
Versatile Solutions for Diverse Industries
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Industry Consulting
News
Blog
2026-04-21
CLIRIK Wins Global Trust | Customer Visits & On-Site Services Boost Win-Win Cooperation
CLIRIK achieves two-way empowerment through global customer visits and on-site services, winning worldwide trust with full-process professional support.
2026-04-21
HGM Series Dolomite Grinding Mill: High-Efficiency Mill Grinder Machine
In recent years, the global powder processing industry has witnessed a sharp rise in demand for ultra-fine powder products, driven by sectors…
2026-04-21
Talcum Powder Manufacturing Process: HGM Pulverizer Machine for Powder
Talcum powder is a widely used industrial material across cosmetics, pharmaceuticals, and plastics, making an efficient talcum powder…
Unfortunately, the information you searched was not found